维生素与矿物质在超重/肥胖人群中的应用价值:体重管理调节机制及临床证据

摘要:超重肥胖人群存在饮食结构不平衡，代谢需求提高或处于慢性炎症状态，大多存在多种维生素矿物质缺乏情况，体内营养素缺乏，会加剧胰岛素抵抗，加重氧化应激，增加脂肪堆积，最终形成身体超重肥胖的恶性循环，对超重肥胖人群，适量补充维生素钙锌等微量营养素补充剂，可以纠正代谢性营养不良，也能规避减重过程中各类营养问题，改变肥胖发生发展的进程。B族维生素、维生素C，加上钙锌等矿物质，可通过多靶点机制实现体重管理。结合现有文献证据，本文梳理维生素矿物质在超重肥胖人群中的应用价值，为肥胖综合干预给出科学有效的治疗依据。

关键词:超重/肥胖;维生素;矿物质;体重管理;代谢调节

Abstract: Overweight and obese populations ofien present unbalanced dietary structures, incrcased metabolic demands, or chronicflammatory states, with most suffering fom deficiencies in yarious vitamins and minerals Insufficient nutrient levels in the body exacerbatesulin resistance, aggravate oxidative stress, and promote fat accumulation, ultimatcly forning a vicious cycle of overwcight and obesity. Foryerwcight and bese individuals, appropriate supplemntation with micronutrients such as vitamins, calcium, and zinc can correct mctabolicnalnutrition, ayoid various nutritional problems during weight loss, and alter the progression of obesity. B vitanins, vitamin C, and mincralsncluding calcium and zinc can achieve wcight management through multi-target mechanisms. Based on existing literature cvidence, this papereviews the application value of vitamins and minerals in overweight and obese populations, providing a scientific and eftective therapeutic basisor comprehensive intervention in obesity.

Key words: Overweight/obesity; Vitamins; Minerals; Weight management; Metabolic regulation